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Reflux

Also known as: Heartburn, gastroesophageal reflux disease, (GERD), "reflux", or acid reflux.

What is it?

Gastroesophageal reflux is also sometimes referred to as acid reflux. It is a disorder where the acid contents of the stomach flow back (reflux) into the esophagus. The esophagus is the tube that connects the throat and stomach. However, the esophagus doesn’t have a protective lining like the stomach, so the acid from gastroesophageal reflux causes the lower part of the esophagus to become inflamed and painful. This condition is called reflux esophagitis.

Who gets it?

Anyone can suffer from gastroesophageal reflux, but it is more likely to affect people who are obese, have a hiatal hernia, experience recurrent vomiting, or have scleroderma. Gastroesophageal reflux may also occur during pregnancy, or in those who have nasogastric tubes.

What causes it?

Acid refluxes from the stomach when the lower esophageal sphincter (LES) isn’t working properly. This sphincter is usually tightly closed and opens only when food passes from the esophagus into the stomach. In addition to the conditions listed under “Who gets it?”, there are a number of factors that can cause the LES to open and let stomach acids reflux. These include eating very large meals, lying down within two to three hours of eating, and taking certain drugs including diazepam, meperidine, theophylline, morphine, prostaglandins, calcium channel blockers, nitrate heart medications, and anticholinergic and adrenergic drugs. If you are prone to acid reflux, eating greasy foods and foods such as chocolate and peppermint can also relax the LES. Caffeine, alcohol, and nicotine may also aggravate acid reflux.

What are the symptoms?

The main symptom of gastroesophageal reflux is heartburn. Other symptoms include cramping, difficult or painful swallowing, pain behind or just below the breastbone, spitting up at night, excessive salivation, sore throat, hoarseness, coughing, shortness of breath, bad breath, and fluid or vomit inhaled into the lungs. Symptoms can appear when you lie down after eating, but are relieved by sitting up. Heartburn can be severe and spread to your neck, jaw, arms, and back. People with heartburn frequently regurgitate stomach contents into their mouths, leaving a bitter taste. If gastroesophageal reflux occurs frequently, it can lead to reflux esophagitis, esophageal narrowing, esophageal ulcer, and Barrett’s syndrome, which is a change in the lining of the esophagus that can lead to esophageal cancer.

How is it diagnosed?

Your doctor will take a complete medical history and review your symptoms. He or she may refer you to a gastroenterologist. Tests used for diagnosis include x-rays, which are taken after a patient drinks a barium solution and lies down with the head lower than the feet, and esophagoscopy, where a flexible viewing tube is inserted into the esophagus for a close examination. A tissue sample (biopsy) may be taken during this test and studied for Barrett’s syndrome. Other tests include esophageal manometry, which measures pressure in the lower esophageal sphincter, and the Bernstein test, which measures the acidity in the esophagus.

What is the treatment?

The main goal of gastroesophageal reflux treatment is the relief of symptoms and prevention of relapses. For mild cases, your doctor may prescribe antacids to take after meals and at bedtime. It may also be helpful to raise the head of your bed to keep the acid flowing away from the esophagus while you sleep. Your doctor may advise you to avoid fatty foods and drinks such as coffee and alcohol that can aggravate this condition. There are drugs called histamine receptor blockers that help to reduce stomach acids. Some people find that proton-pump inhibitors are more effective at inhibiting acid production than the histamine receptor blockers. There are also drugs, called prokinetic or motility drugs, that make the lower esophageal sphincter close more tightly. Additional drug therapy, including omepraxole or lansoprazole, can quickly heal esophageal inflammation. A narrowed esophagus is treated with drug therapy and dilation. Surgery is only recommended if the symptoms don’t respond to other treatments. Less than 25% of people with gastroesophageal reflux require surgery.

Surgical Treatment

During the minimally invasive "reflux" procedure, our specialists use pencil-thin cameras to see a detailed picture of your body. From there, they insert other tiny instruments through small incisions into the body to surgically correct the disorder. A new, more effective esophageal "valve" is created by wrapping the stomach around the esophagus. The surgery is called Laparoscopic Nissen Fundoplication.

Since the procedure is performed through dime-size incisions, minimally invasive surgery is easier on you. Smaller incisions and less disruption inside the body mean less discomfort, a shorter hospital stay and faster recovery. The small incisions also provide better cosmetic results. Patients who undergo the procedure report immediate relief from painful heartburn, regurgitation, hoarseness, chronic coughing, and swallowing difficulties. Most patients see these improvements while stopping all medications for reflux including antacids, H2 blockers, proton-pump inhibitors, and pro-motility medications. And...they can eat foods that they have not dared to try for years!

We are committed to improving your health

Taking a team approach to care, we work closely with patients' physicians and gastroenterology specialists to provide comprehensive care. A thorough medical evaluation is necessary prior to surgery. The evaluation may include an upper gastrointestinal x-ray and an upper gastrointestinal endoscopy as well as tests that measure pressure and function of the esophagus and stomach. You can expect to go home one or two days after the surgery. Together with your physician, we will provide follow-up care until you are fully recovered.

Self-care tips

If you have been diagnosed gastroesophageal reflux disease (GERD), follow your doctor’s instructions for care and treatment. Maintain a healthy diet, exercise regularly, and avoid eating large meals, drinking alcohol, and smoking cigarettes. Wearing clothing that fits loosely around the stomach can help stop stomach acids from refluxing. You can help prevent gastroesophageal reflux by eating frequent, small meals; remaining upright for at least 3 hours after meals; and avoiding stress during meals or soon after eating.


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice. 

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This page was last updated on October 31, 2006
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