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Testicular Cancer

What is it?

Testicular cancer is a disease caused by the uncontrolled growth of abnormal cells in the testes, or testicles. The two testes are located below the penis inside a protective thin-skinned sac, called the scrotum. The testes produce sperm and form the male hormone testosterone. When abnormal cells grow uncontrolled in the testes, they create a lump or tumor. Testicular cancer is classified as two different types, seminomas and non-seminomas.

Who gets it?

Testicular cancer is the most common type of cancer in men under the age of 35, with most cases occurring before age 30.

What causes it?

The cause of testicular cancer is unknown. However, men whose testes did not descend into the scrotum by age three are more likely to develop testicular cancer than men whose testes did descend by that age. Normally, the testes move down from inside the abdomen into the scrotum before birth. An undescended testicle is a condition where one or both testes remain inside the abdomen. This condition can be surgically corrected, but the man still carries an increased risk of testicular cancer. Higher rates of testicular cancer have also been noted in men with HIV infection.

What are the symptoms?

Signs of testicular cancer include a lump in either testicle, which may or may not be painful and may cause the testes to feel heavy. Some types of tumors in the testes can cause a man’s breast area to enlarge. If the cancer has spread to other areas of the body (metastasized), you may experience low back pain, difficulty urinating, a persistent cough, and difficulty breathing.

How is it diagnosed?

Your doctor will take a complete medical history and perform a complete physical exam, specifically checking your testes for lumps. An ultrasound scan of the scrotum, abdomen, and pelvic areas can help determine where the lump is located and if the cancer has spread. Your doctor may also order blood tests because men with testicular cancer usually have high levels of alpha-fetoprotein and human chorionic gonadotropin. If your symptoms include coughing and breathing difficulties, your doctor may also want you to have a chest x-ray. Bone scans and x-ray of the lymphatic vessels may be ordered. If a lump is found on either testicle, you will receive a local anesthetic and your doctor will take a small tissue sample (biopsy) from the lump to confirm a diagnosis. This procedure does not harm the testes.

What is the treatment?

Testicular cancer is treated by an oncologist, a cancer specialist. The cancerous testicle will be removed surgically. However, the remaining testicle will provide sufficient amounts of male hormones so you will still be able to father children. Following the surgery, you may need chemotherapy (anti-cancer drugs) and/or radiation therapy to destroy any cancer cells that may have spread. Treatment advances have made testicular cancer curable. In fact, the cure rate for testicular cancer that hasn't spread is as high as 95%. Your chances for a complete recovery depend upon how early your cancer was diagnosed, whether the cancer has spread, and the size and type of the tumor. After your treatment, you will need to have checkups on a monthly basis for one year, then at regular intervals to make sure the cancer has not returned. Finding a recurrence as soon as possible greatly improves your chances for recovery.

Self-care tips

Because testicular cancer has a high cure rate if caught early, it is extremely important to examine your testicles monthly for lumps and to have regular physical exams in your doctor’s office. Report even the smallest lump to your doctor. If you are a smoker, keep in mind that smoking increases the risk for many different types of cancer.
 


This information has been designed as a comprehensive and quick reference guide written by our health care reviewers.  The health information written by our authors is intended to be a supplement to the care provided by your physician.  It is not intended nor implied to be a substitute for professional medical advice. 

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This page was last updated on October 31, 2006
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